Clinicopathologic Features of IgA-Dominant Postinfectious Glomerulonephritis

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منابع مشابه

Clinicopathologic Features of IgA-Dominant Postinfectious Glomerulonephritis

BACKGROUND IgA-dominant acute postinfectious glomerulonephritis (APIGN) is a recently recognized morphologic variant of APIGN, but its clinicopathologic features were not clearly characterized. We will present demographic, clinical and renal biopsy findings from seven patients with IgA-dominant APIGN with a literature review. METHODS All renal biopsy specimens (n=1,119) processed by the Depar...

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IgA-dominant postinfectious glomerulonephritis: a new twist on an old disease.

IgA-dominant acute postinfectious glomerulonephritis (APIGN) is an increasingly recognized morphologic variant of APIGN, particularly in the elderly. In contrast to classic APIGN, in which there is typically glomerular deposition of IgG and C3 or C3 only, IgA is the sole or dominant immunoglobulin in IgA-dominant APIGN. Because the vast majority of reported cases occur in association with staph...

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IgA-Dominant Acute Postinfectious Glomerulonephritis Presenting as Acute Renal Failure in a Kidney Transplant Recipient

Manish Anand, Juan Pablo Arroyo, Hassan Alhalabi, Timothy Thayer, Mark Lusco, Anthony Langone and Beatrice P. Concepcion Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; and Department of Pathology, Micro...

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Postinfectious glomerulonephritis in the elderly.

Postinfectious glomerulonephritis (PIGN) is primarily a childhood disease that occurs after an upper respiratory tract infection or impetigo; its occurrence in older patients is not well characterized. Here, we report 109 cases of PIGN in patients ≥65 years old diagnosed by renal biopsy. The male to female ratio was 2.8:1. An immunocompromised background was present in 61%, most commonly diabet...

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Immune profile of IgA-dominant diffuse proliferative glomerulonephritis

The diagnosis of IgA-dominant post-infectious glomerulonephritis (PIGN) may be challenging, as it must be differentiated from that of active IgA nephropathy. Predominant clinicopathologic features of IgA-dominant PIGN substantially overlap with those of active IgA nephropathy. Here, we present a case of a 67-year-old woman with rapidly rising serum creatinine, proteinuria and severe hypertensio...

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ژورنال

عنوان ژورنال: Korean Journal of Pathology

سال: 2012

ISSN: 1738-1843,2092-8920

DOI: 10.4132/koreanjpathol.2012.46.2.105